Premature Ejaculation

Premature Ejaculation or Erectile Dysfunction? How to Tell the Difference and When Both Occur

By Gregory S. Parries, MD, PhD. | Medically Reviewed by Christopher W. Boelter, MD | Last updated 2026-07-14 Men often come to a urology visit knowing that something is wrong but not knowing what to call it. “I lose control too quickly.” “I cannot stay hard.” “I rush because I am afraid the erection will […]

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The Science of Ejaculation: How Serotonin, Nerves and the Pelvic Floor Control Climax

By Gregory S. Parries, MD, PhD. | Medically Reviewed by Christopher W. Boelter, MD | Last updated 2026-07-14 Ejaculation is not a switch located in the penis, prostate, spinal cord, or brain. It is a sequence. Sensory information must be detected, interpreted, and integrated. Autonomic nerves then move sperm and glandular fluids into the urethra.

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Lifelong vs Acquired Premature Ejaculation: Causes, Symptoms and Clinical Differences

By Gregory S. Parries, MD, PhD. | Medically Reviewed by Christopher W. Boelter, MD | Last updated 2026-07-14 Premature ejaculation (PE) is often described as though it were one condition with one cause. Clinically, that is not accurate. A man who has ejaculated earlier than desired since his first sexual experiences presents a different diagnostic

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Dapoxetine (Priligy) for Premature Ejaculation: Dosage, Timing, Side Effects

By John K. Matsuura, MD | Medically Reviewed by Christopher W. Boelter, MD | Last reviewed 2026-07-15 What Dapoxetine Is Used For Dapoxetine is a short-acting SSRI used in some countries as an on-demand treatment for premature ejaculation. Unlike many antidepressant SSRIs that are taken daily, dapoxetine was developed for use before sexual activity in

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