PDE5 Inhibitors in Modern Medicine: A Comprehensive Review of Mechanism, Efficacy, and Clinical Application
By John K. Matsuura, MD | Medically Reviewed by Christopher W. Boelter, MD |Last updated 08 July 2025 Understanding Erectile Dysfunction and the Rise of PDE5 Inhibitors Erectile dysfunction (ED) is one of the most common sexual health disorders affecting men worldwide. Defined as the persistent inability to achieve or maintain an erection sufficient for satisfactory sexual performance, ED significantly impacts […]